BEGIN:VCALENDAR VERSION:2.0 PRODID:-//Sabre//Sabre VObject 4.5.7//EN CALSCALE:GREGORIAN BEGIN:VTIMEZONE TZID:Europe/Zurich X-LIC-LOCATION:Europe/Zurich TZURL:http://tzurl.org/zoneinfo/Europe/Zurich BEGIN:DAYLIGHT TZOFFSETFROM:+0100 TZOFFSETTO:+0200 TZNAME:CEST DTSTART:19810329T020000 RRULE:FREQ=YEARLY;BYMONTH=3;BYDAY=-1SU END:DAYLIGHT BEGIN:STANDARD TZOFFSETFROM:+0200 TZOFFSETTO:+0100 TZNAME:CET DTSTART:19961027T030000 RRULE:FREQ=YEARLY;BYMONTH=10;BYDAY=-1SU END:STANDARD END:VTIMEZONE BEGIN:VEVENT UID:news535@chemie.unibas.ch DTSTAMP;TZID=Europe/Zurich:20240219T100517 DTSTART;TZID=Europe/Zurich:20240409T170000 SUMMARY:Privileged Chiral Catalysts: Selectivity and Generality in Enantios elective Catalysis (Camille & Henry Dreyfus Lecture) DESCRIPTION:Privileged chiral scaffolds—structures that have been demonst rated to induce high levels of enantioselectivity across a variety of mech anistically distinct reactions—have proven profoundly enabling to the di scovery of new asymmetric catalytic reactions. This lecture will outline t he development of a specific\, new class of privileged chiral catalysts: d ual H-bond donors (HBDs) bearing aryl-pyrrolidino-tert-leucine motifs. The se HBD catalysts have proven broadly useful in a variety of C–C and C– heteroatom bond-forming processes\, with enantioselectivity dictated prima rily through selective stabilizing non-covalent interactions. Detailed cas e studies on the mechanism of enantioinduction with aryl-pyrrolidino-tert- leucine HBDs will be presented\, highlighting the cooperative features of these simple organic molecules that are likely responsible for the privile ged nature of this scaffold.\\r\\nCamille & Henry Dreyfus Lectureship In m emory of the Dreyfus brothers\, the Camille and Henry Dreyfus Foundation I nc. has established the Camille & Henry Dreyfus Lectureship at the Univers ity of Basel [https://chemie.unibas.ch/de/aktuelles/veranstaltungen/dreyfu s-lectureship/]. The annual Lectureship brings a leading chemist from the United States to the Basel campus to deliver a series of talks\, and to me et with faculty and students in order to enhance the relationship between Swiss and U.S. science. X-ALT-DESC:

Privileged chiral scaffolds—structures that have been demon strated to induce high levels of enantioselectivity across a variety of me chanistically distinct reactions—have proven profoundly enabling to the discovery of new asymmetric catalytic reactions. This lecture will outline the development of a specific\, new class of privileged chiral catalysts: dual H-bond donors (HBDs) bearing aryl-pyrrolidino-tert-leucine motifs. These HBD catalysts have proven broadly useful in a variety of C –C and C–heteroatom bond-forming processes\, with enantioselectivity d ictated primarily through selective stabilizing non-covalent interactions. Detailed case studies on the mechanism of enantioinduction with aryl-pyrr olidino-tert-leucine HBDs will be presented\, highlighting the co operative features of these simple organic molecules that are likely respo nsible for the privileged nature of this scaffold.

\n

Camille &\; Henry Dreyfus Lectureship
In memory of the Dreyfus brothers\, the Camille and Henry Dreyfus Foundation Inc. has established t he Camille &\; Henry Dreyfus Lectureship at the University o f Basel. The annual Lectureship brings a leading chemist from the Unit ed States to the Basel campus to deliver a series of talks\, and to meet w ith faculty and students in order to enhance the relationship between Swis s and U.S. science.

DTEND;TZID=Europe/Zurich:20240409T183000 END:VEVENT END:VCALENDAR