Structure and function of proteins: Pseudo-contact shifts as a valuable tool in NMR spectroscopy
Researchers of the Biozentrum and the Department of Chemistry have developed a novel NMR method with which they could track the dynamics of the activation of a G-protein-coupled receptor at the molecular level for the first time. These…
New spectroscopic methods for the quantitative detection of functional groups on the nanoparticles surface
The combination of nanoparticles with biologically active molecules such as antibodies offers promising applications in the diagnosis and treatment of various diseases. In order to design these so-called bioconjugated nanoparticles in a…Modification of very stable chemical bonds in organic molecules
A research team at the University of Basel has developed a new method to specifically alter certain very stable chemical bonds in organic molecules. In the long term, this discovery could make the production of medicines and other chemical…
Register Now: 2025 Repurposed & Artificial Enzymes Conference, 26-29 June 2025
A conference reflecting the remarkable achievements in the fields of repurposed an artificial enzymes with the aim to complement the catalytic prowess of natural enzymes.
Molecules in full gallop
An interdisciplinary team of scientists investigates how exactly individual biomolecules move around. One of the tricks the researchers use involves tiny pores that only allow one molecule to slip through at a time.
Synthetic cells emulate natural cellular communication
A research team from the University of Basel has succeeded in synthesizing simple, environmentally sensitive cells complete with artificial organelles. For the first time, the researchers have also been able to emulate natural cell-cell…
Single-molecule detection of CRISPR-Cas second messengers using nanopores
Second messengers are molecules with a central role in cellular signaling and communication. For the first time, an interdisciplinary team led by Sonja Schmid achieved the detection of CRISPR-Cas-produced messengers with single-molecule…
New approach in the synthesis of complex natural substances
They are found as fragrances in cosmetics or as flavorings in food, and form the basis of new medications: Terpenes are natural substances that occur in plants, insects and sea sponges. They are difficult to produce synthetically. However,…
Using light to produce medication and plastics more efficiently
Anyone who wants to produce medication, plastics or fertilizer using conventional methods needs heat for chemical reactions – but not so with photochemistry, where light provides the energy. The process to achieve the desired product also…