Publications

Liao, C. und Seebeck, F. P. (2019) «S-adenosylhomocysteine as a methyl transfer catalyst in biocatalytic methylation reactions», Nature Catalysis . Springer Nature , 2(8), S. 696-701. doi: 10.1038/s41929-019-0300-0.   edoc
Leisinger, F., Burn, R., Meury, M., Lukat, P. und Seebeck, F. P. (2019) «Structural and Mechanistic Basis for Anaerobic Ergothioneine Biosynthesis», Journal of the American Chemical Society. American Chemical Society, 141 (17), S. 6906-6914. doi: 10.1021/jacs.8b12596.   edoc | Open Access
Maurer, A., Leisinger, F., Lim, D. und Seebeck, F. P. (2019) «Structure and Mechanism of Ergothionase from Treponema denticola», Chemistry - A European Journal. Wiley, 25(44), S. 10298-10303. doi: 10.1002/chem.201901866.   edoc | Open Access
Miarzlou, D. A., Leisinger, F., Joss, D., Häussinger, D. und Seebeck, F. P. (2019) «Structure of formylglycine-generating enzyme in complex with copper and a substrate reveals an acidic pocket for binding and activation of molecular oxygen», Chemical Science. Royal Society of Chemistry, 10(29), S. 7049-7058. doi: 10.1039/c9sc01723b.   edoc | Open Access
Lim, D., Gründemann, D. und Seebeck, F. P. (2019) «Total Synthesis and Functional Characterization of Selenoneine», Angewandte Chemie International Edition. Wiley, 58(42), S. 15026-15030. doi: 10.1002/anie.201908967.   edoc
Liao, C. und Seebeck, F. P. (2019) «In vitro reconstitution of bacterial DMSP biosynthesis», Angew. Chemie Int. Ed, 58(11), S. 3553-3556.   edoc
Stampfli, A. R., Goncharenko, K. V., Meury, M., Dubey, B. N., Schirmer, T. und Seebeck, F. P. (2019) «An Alternative Active Site Architecture for O2 Activation in the Ergothioneine Biosynthetic EgtB from Chloracidobacterium thermophilum», Journal of American Chemical Society. American Chemical Society, 141(13), S. 5275-5285. doi: 10.1021/jacs.8b13023.   edoc | Open Access
Misson, L., Burn, R., Vit, A., Hildesheim, J., Beliaeva, M. A., Blankenfeldt, W. und Seebeck, F. P. (2018) «Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD», ACS Chemical Biology. American Chemical Society, 13(5), S. 1333-1342. doi: 10.1021/acschembio.8b00127.   edoc | Open Access
Castellano, I. und Seebeck, F. P. (2018) «On ovothiol biosynthesis and biological roles: from life in the ocean to therapeutic potential», Natural Product Reports. The Royal Society of Chemistry, 35(12), S. 1241-1250. doi: 10.1039/c8np00045j.   edoc | Open Access
Gamage, A. M., Liao, C., Cheah, I. K., Chen, Y., Lim, D. R. X., Ku, J. W. K., Chee, R. S. L., Gengenbacher, M., Seebeck, F. P., Halliwell, B. und Gan, Y.-H. (2018) «The proteobacterial species Burkholderia pseudomallei produces ergothioneine, which enhances virulence in mammalian infection», FASEB Journal. Federation of American Society of Experimental Biology , 32(12), S. 6395-6409. doi: 10.1096/fj.201800716.   edoc
Knop, M., Dang, T. Q., Jeschke, G. und Seebeck, F. P. (2017) «Copper is a Cofactor of the Formylglycine-Generating Enzyme», ChemBioChem. Wiley, 18(2), S. 161-165. doi: 10.1002/cbic.201600359.   edoc | Open Access
Meury, M., Knop, M. und Seebeck, F. P. (2017) «Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycine-Generating Enzyme», Angewandte Chemie International Edition. Wiley, 56(28), S. 8115-8119. doi: 10.1002/anie.201702901.   edoc | Open Access
Knop, M., Lemnaru, R. und Seebeck, F. P. (2017) «Mutation of Conserved Residues Increases in Vitro Activity of the Formylglycine-Generating Enzyme», ChemBioChem. Wiley, 18(17), S. 1755-1761. doi: 10.1002/cbic.201700174.   edoc
Faponle, A. S., Seebeck, F. P. und de Visser, S. P. (2017) «Sulfoxide Synthase versus Cysteine Dioxygenase Reactivity in a Nonheme Iron Enzyme», Journal of the American Chemical Society. American Chemical Society, 139(27), S. 9259-9270. doi: 10.1021/jacs.7b04251.   edoc | Open Access
Burn, R., Misson, L., Meury, M. und Seebeck, F. P. (2017) «Anaerobic Origin of Ergothioneine», Angewandte Chemie International Edition. Wiley, 56(41), S. 12508-12511. doi: 10.1002/anie.201705932.   edoc
Liao, C. und Seebeck, F. P. (2017) «Convergent Evolution of Ergothioneine Biosynthesis in Cyanobacteria», ChemBioChem. Wiley, 18(21), S. 2115-2118. doi: 10.1002/cbic.201700354.   edoc
Goncharenko, K. und Seebeck, F. P. (2016) «Conversion of a non-heme iron-dependent sulfoxide synthase into a thiol dioxygenase by a single point mutation», Chemical Communications . Royal Society of Chemistry, 52(9), S. 1945-1948. doi: 10.1039/c5cc07772a.   edoc | Open Access
Vit, A., Mashabela, G., Blankenfeldt, W. und Seebeck, F. P. (2015) «Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC», ChemBioChem. Wiley, 16(10), S. 1490-1496. doi: 10.1002/cbic.201500168.   edoc | Open Access
Knop, M., Engi, P., Lemnaru, R. und Seebeck, F. P. (2015) «In Vitro Reconstitution of Formylglycine-Generating Enzymes Requires Copper(I)», ChemBioChem. Wiley, 16(15), S. 2147-2150. doi: 10.1002/cbic.201500322.   edoc | Open Access
Goncharenko, K. V., Vit, A., Blankenfeldt, W. und Seebeck, F. P. (2015) «Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway», Angewandte Chemie International Edition. Wiley, 54(9), S. 2821-2824. doi: 10.1002/anie.201410045.   edoc | Open Access
Vit, A., Misson, L., Blankenfeldt, W. und Seebeck, F. P. (2015) «Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis», ChemBioChem. Wiley, 16(1), S. 119-125. doi: 10.1002/cbic.201402522.   edoc
Vit, A., Misson, L., Blankenfeldt, W. und Seebeck, F. (2014) «Crystallization and preliminary X-ray analysis of the ergothioneine-biosynthetic methyltransferase EgtD», Acta Crystallographica Section F: Structural Biology and Crystallization Communications. International Union of Crystallography , 70(5), S. 676-680. doi: 10.1107/S2053230X1400805X.   edoc | Open Access
Seebeck, F. (2013) «Thiohistidine biosynthesis», Chimia. Schweizerische Chemische Gesellschaft, 67(5), S. 333-336. doi: 10.2533/chimia.2013.333.   edoc | Open Access
Mashabela, G. und Florian, S. (2013) «Substrate specificity of an oxygen dependent sulfoxide synthase in ovothiol biosynthesis», Chemical Communications. Royal Society of Chemistry, 49(70), S. 7714-7716. doi: 10.1039/c3cc42594k.   edoc | Open Access
Amrein, B., Schmid, M., Collet, G., Cuniasse, P., Gilardoni, F., Seebeck, F. P. und Ward, T. R. (2012) «Identification of two-histidines one-carboxylate binding motifs in proteins amenable to facial coordination to metals», Metallomics. Royal Society of Chemistry, 4(4), S. 379-388. doi: 10.1039/C2MT20010D.   edoc
Hofmann, F., Szostak, J. W. und Seebeck, F. P. (2012) «In vitro selection of functional lantipeptides», Journal of the American Chemical Society. American Chemical Society, 134(19), S. 8038-8041. doi: 10.1021/ja302082d.   edoc