Publications
Sauter, B. et al. (2025) “Challenges and Opportunities in DNA Encoded Library Screens”, CHIMIA, 79(3), pp. 158–161. Available at: 10.2533/chimia.2025.158.
Cai, P. et al. (2025) “A method to identify small molecule/protein pairs susceptible to protein ubiquitination by the CRBN E3 ligase”. Cambridge University Press (Chemrxiv). Available at: 10.26434/chemrxiv-2024-8v8km-v2.
Cai, P. et al. (2024) “A method to identify small molecule/protein pairs susceptible to protein ubiquitination”. Cambridge University Press (Chemrxiv). Available at: 10.26434/chemrxiv-2024-8v8km.
Kozicka, Z. et al. (2024) “Design principles for cyclin K molecular glue degraders”, Nature Chemical Biology, 20(1), pp. 93–102. Available at: 10.1038/s41589-023-01409-z.
Jauslin, W.T. et al. (2024) “Correction: A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα”, Chemical Science, 15(4), pp. 1520–1520. Available at: 10.1039/d4sc90011a.
Gillingham, D.G., Sauter, B. (2024) “3.2.3.1 Macrocyclic DELs”, in J. Scheuermann and Y. Li (eds.), A. Fürstner et al. (trans.) DNA-Encoded Libraries. 1st ed. Stuttgart: Georg Thieme Verlag KG (Science of Synthesis), p. 561-. Available at: 10.1055/sos-sd-241-00235.
Jauslin, W.T. et al. (2023) “A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα”, Chemical Science, 15(2), pp. 683–691. Available at: 10.1039/d3sc04629j.
Schneider, L.A. et al. (2023) “Recording Binding Information Directly into DNA-Encoded Libraries Using Terminal Deoxynucleotidyl Transferase”, Journal of the American Chemical Society, 145(38), pp. 20874–20882. Available at: 10.1021/jacs.3c05961.
Murawska, G.M. et al. (2022) “Repurposing the Damage Repair Protein Methyl Guanine Methyl Transferase as a Ligand Inducible Fusion Degron”, ACS Chemical Biology [Preprint]. Available at: 10.1021/acschembio.1c00771. edoc
Sauter, B. et al. (2021) “An assessment of the mutational load caused by various reactions used in DNA encoded libraries”, Bioorganic & Medicinal Chemistry, 52, p. 116508. Available at: 10.1016/j.bmc.2021.116508. edoc
Cai, P. et al. (2021) “Building Boron Heterocycles into DNA-Encoded Libraries”, Organic letters, 23(22), pp. 8772–8776. Available at: 10.1021/acs.orglett.1c03262. edoc
Kilaj, A. et al. (2020) “Quantum-chemistry-aided identification, synthesis and experimental validation of model systems for conformationally controlled reaction studies: separation of the conformers of 2,3-dibromobuta-1,3-diene in the gas phase”, Physical Chemistry Chemical Physics, 22(24), pp. 13431–13439. Available at: 10.1039/d0cp01396j. edoc | Open Access
Sauter, B., Gillingham, D. (2020) “DNA Damaging Agents in Chemical Biology and Cancer”, Chimia, 74(9), pp. 693–698. Available at: 10.2533/chimia.2020.693. edoc
Słabicki, M. et al. (2020) “The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K”, Nature, 585(7824), pp. 293–297. Available at: 10.1038/s41586-020-2374-x. edoc
Stress, C.J. et al. (2019) “Eine DNA‐kodierte Molekülbibliothek mit Elementen natürlicher Makrocyclen”, Angewandte Chemie, 131(28), pp. 9671–9675. Available at: 10.1002/ange.201902513.
Räz, M.H. et al. (2019) “High Sensitivity of Human Translesion DNA Synthesis Polymerase κ to Variation in O6-Carboxymethylguanine Structures”, ACS Chemical Biology, 14(2), pp. 214–222. Available at: 10.1021/acschembio.8b00802. edoc | Open Access
Stress, C.J. et al. (2019) “A DNA-Encoded Chemical Library Incorporating Elements of Natural Macrocycles”, Angewandte Chemie International Edition, 58(28), pp. 9570–9574. Available at: 10.1002/anie.201902513. edoc | Open Access
Wang, Y. et al. (2019) “Nanopore Sequencing Accurately Identifies the Mutagenic DNA Lesion O; 6; -Carboxymethyl Guanine and Reveals Its Behavior in Replication”, Angewandte Chemie International Edition, 58(25), pp. 8432–8436. Available at: 10.1002/anie.201902521. edoc | Open Access
Gillingham, D., Rasale, D. (2018) “Direct and Selective Modification of RNA - An Open Challenge in Nucleic Acid Chemistry”, Chimia, 72(11), pp. 777–781. Available at: 10.2533/chimia.2018.777. edoc
Zhao, J. et al. (2018) “An artificial metalloenzyme for carbene transfer based on a biotinylated dirhodium anchored within streptavidin”, Catalysis science & technology, 8(9), pp. 2294–2298. Available at: 10.1039/c8cy00646f. edoc | Open Access
Sauter, B., Gillingham, D. (2018) “Profiling the Nucleobase and Structure Selectivity of Anticancer Drugs and other DNA Alkylating Agents by RNA Sequencing”, ChemBioChem, 19(15), pp. 1638–1642. Available at: 10.1002/cbic.201800235. edoc | Open Access
Rasale, D. et al. (2018) “A new water soluble copper N-heterocyclic carbene complex delivers mild O6G-selective RNA alkylation”, Chemical Communications, 54(66), pp. 9174–9177. Available at: 10.1039/c8cc04476g. edoc | Open Access
Geigle, S. et al. (2017) “Copper carbenes alkylate guanine chemoselectively through a substrate directed reaction”, Chemical Science, 8(1), pp. 499–506. Available at: 10.1039/c6sc03502g. edoc | Open Access
Gillingham, D., Sauter, B. (2017) “Genomic Studies Reveal New Aspects of the Biology of DNA Damaging Agents”, ChemBioChem, 18(24), pp. 2368–2375. Available at: 10.1002/cbic.201700520. edoc
Gillingham, D., Geigle, S., von Lilienfeld, O.A. (2016) “Properties and reactivity of nucleic acids relevant to epigenomics, transcriptomics, and therapeutics”, Chemical Society Reviews, 45(9), pp. 2637–55. Available at: 10.1039/c5cs00271k. edoc | Open Access
Fei, N., Sauter, B., Gillingham, D. (2016) “The pKa of Bronsted acids controls their reactivity with diazo compounds”, Journal of the Chemical Society, Chemical Communications, 52(47), pp. 7501–7504. Available at: 10.1039/c6cc03561b. edoc | Open Access
Gillingham, D. (2016) “The role of boronic acids in accelerating condensation reactions of [small alpha]-effect amines with carbonyls”, Organic & Biomolecular Chemistry, 14(32), pp. 7606–7609. Available at: 10.1039/c6ob01193d. edoc | Open Access
Stress, C., Schmidt, P., Gillingham, D. (2016) “Comparison of boron-assisted oxime and hydrazone formations leads to the discovery of a fluorogenic variant”, Organic & Biomolecular Chemistry, 14(24), pp. 5529–33. Available at: 10.1039/c6ob00168h. edoc | Open Access
Tishinov, K., Gillingham, D. (2015) “Synthesis of New Alkylated Mononucleotide Analogues and Their Repair Proficiency by the Prokaryotic DNA Repair Protein AlkB”, Synlett, 26(19), pp. 2720–2723. Available at: 10.1055/s-0035-1560491. edoc
Gillingham, D., Shahid, R. (2015) “Catalysts for RNA and DNA modification”, Current Opinion in Chemical Biology, 25, pp. 110–4. Available at: 10.1016/j.cbpa.2014.12.025. edoc
Bachmann, D. et al. (2015) “Modular ligands for dirhodium complexes facilitate catalyst customization”, Advanced Synthesis and Catalysis, 357(9), pp. 2033–2038. Available at: 10.1002/adsc.201500050. edoc | Open Access
Schmidt, P., Stress, C., Gillingham, D. (2015) “Boronic acids facilitate rapid oxime condensations at neutral pH”, Chemical Science, 6(6), pp. 3329–3333. Available at: 10.1039/c5sc00921a. edoc | Open Access
Fei, N. et al. (2014) “Catalytic carbene transfer allows the direct customization of cyclic purine dinucleotides”., Chemical Communications, 50(62), pp. 8499–502. Available at: 10.1039/c4cc01919a. edoc | Open Access
Schmidt, P. et al. (2014) “Dialdehydes Lead to Exceptionally Fast Bioconjugations at Neutral pH by Virtue of a Cyclic Intermediate”, Angewandte Chemie International Edition, 53(41), pp. 10928–31. Available at: 10.1002/anie.201406132. edoc
Bachmann, D.G., Wittwer, C.C., Gillingham, D.G. (2013) “Stereoselective Heck Reactions with Vinyl Sulfoxides, Sulfides and Sulfones”, Advanced Synthesis and Catalysis, 355(18), pp. 3703–3707. Available at: 10.1002/adsc.201300678. edoc
Gillingham, D., Tishinov, K. (2013) “Synthesis of nucleic acid polymers with non-canonical nucleobases”, Synlett, 24(8), pp. 893–897. Available at: 10.1055/s-0032-1318493. edoc
Gillingham, D., Fei, N. (2013) “Catalytic X-H insertion reactions based on carbenoids”, Chemical Society Reviews, 42(12), pp. 4918–31. Available at: 10.1039/c3cs35496b. edoc | Open Access
Tishinov, K., Fei, N., Gillingham, D. (2013) “Cu(I)-catalysed N-H insertion in water: a new tool for chemical biology”, Chemical Science, 4(12), pp. 4401–4406. Available at: 10.1039/c3sc51363g. edoc | Open Access
Tishinov, K. et al. (2012) “Structure-selective catalytic alkylation of DNA and RNA”, Angewandte Chemie International Edition, 51(48), pp. 12000–4. Available at: 10.1002/anie.201205201. edoc
Gillingham, D., Martinez, A., Pianowski, Z. (2012) “Report from the 47th EUCHEMS Conference on Stereochemistry : The Bürgenstock Conference”, Chimia, 66(11), pp. 873–875. Available at: 10.2533/chimia.2012.873. edoc | Open Access
Stallforth, P. et al. (2012) “De novo chemoenzymatic synthesis of sialic acid”, Chemical Communications, 48(98), pp. 11987–9. Available at: 10.1039/c2cc37305j. edoc
Clemens, M. et al. (2011) “An Artificial Metalloenzyme for Olefin Metathesis”, Journal of the Chemical Society, Chemical Communications, 47(44), pp. 12068–12070. Available at: 10.1039/c1cc15005g. edoc